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Medical Scope Journal (MSJ)
Published by Universitas Sam Ratulangi
ISSN : -     EISSN : 27153312     DOI : https://doi.org/10.35790/msj
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Nursing Public Health
Medical Scope Journal (MSJ) diterbitkan oleh Perhimpunan Ahli Anatomi Indonesia (PAAI) Komisariat Manado bekerjasama dengan Fakultas Kedokteran Universitas Sam Ratulangi dua kali setahun pada bulan Juni dan Desember. Tulisan yang dimuat dapat berupa artikel telaah (review article), hasil penelitian, dan laporan kasus dalam bidang ilmu kedokteran baik dalam bahasa Indonesia maupun dalam bahasa Inggris.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 23 Documents
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Search results for , issue "Vol. 6 No. 1 (2024): Medical Scope Journal" : 23 Documents clear
Transurethral Vaporization of Bladder Neck Using Holmium Laser: First Experience in Manado Mahesa Krishna; Eko Arianto; Ari Astram; Frendy Wihono; Christof Toreh
Medical Scope Journal Vol. 6 No. 1 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i1.46491

Abstract

Abstract: Bladder neck contracture (BNC) is a potential complication after radical prostatectomy (RP). This may be a result of inadequate approximation at the time of surgery, urinary extravasation, or distraction of the bladder neck from a hematoma. Patients commonly complains of a poor urinary stream or prolonged unexplained incontinence. Treatment of BNC requires a tailored approach and can range from simple, office-based procedures to complex surgical reconstruction. We reported a case of 81-year-old male complaining urine retention for one month. The patient had previous open prostate procedure a year prior. On examination, neurogenic causes were excluded. Retrograde ureterocystography revealed bladder neck contracture. Patient was diagnosed as bladder neck contracture post open prostatectomy surgery. Transurethral holmium laser vaporization with 800 micrometre, 20 Hz frequency and 4,5 Joule of power. through a ureteroscope was performed. Two-way Folley catheter 18Fr was inserted without irrigation. Patient was discharged post-surgery two days after catheter removal and spontaneous micturition. Endoscopic balloon dilatation with incision appears to offers promising result in the management of BNC. The consideration of using transurethral vaporization with holmium laser modality was the first procedure ever done in Manado. In conclusion, TUVP is one of the alternatives, minimally invasive procedures to treat BNC. The use of holmium laser for the incision of bladder neck is another alternative to treat BNC with great outome proven by the length of stay (LOS) of two days after the procedure was done. Keywords: bladder neck contracture; transurethral vaporization; holmium laser; post prostatectomy
Penilaian Parut Hipertrofi Luka Bakar Berdasarkan Patient and Observer Scar Assessment Scales (POSAS) Eko S. Sinaga; Mendy Hatibie; Maximillian C. Oley; Fredrik G. Langi
Medical Scope Journal Vol. 6 No. 1 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i1.46566

Abstract

Abstract: Hypertrophic scar of burn can occur due to the imbalances in the wound healing process that can affect the quality of life. Patient and Observer Scar assessment Scales (POSAS) is an assessment instrument both from the patient and the observer. This study aimed to assess hypertrophic scars with POSAS. This was an observational and analytical study with a cross sectional design. Samples were patient with burns admitted to Prof. Dr. R. D. Kandou Hospital, Manado, and its network hospitals. The assessment was carried out directly when the patients being admitted to the hospital. Each patient who met the requirements had demographic and clinical data taken. Subsequent assessments were carried out at one month and six months after the initial treatment procedure. The results obtained 30 patients with burn dominated by females (63%). The most common degree of burns was superficial-middermal (67%). The assessment of POSAS by doctors and patients tended to be the same and both decreased in the first month and the sixth month after initial treatment procedure with a mean value of the total pre- initial treatment procedure score of 51.3±12.1; 1st month 44.2±9.5; 6th month 30.3±5.9. In conclusion, the evaluation of burns that produce acceptable hypertrophic scars using the POSAS score shows similarities in the assessment of observers and patients. Moreover, precautions at the beginning of the observation will affect the POSAS score Keywords: burn; hypertrophic scar; Patient and Observer Scar Assessment Scales   Abstrak: Parut hipertrofi paska luka bakar dapat terjadi karena ketidakseimbangan pada proses penyembuhan luka yang dapat memengaruhi kualitas hidup. Patient and Observer Scar Assessment Scales (POSAS) merupakan instrumen penilaian parut baik dari pasien maupun observer. Penelitian ini bertujuan untuk menilai parut hipertrofi dengan menggunakan POSAS. Jenis penelitian ialah observasional analitik dengan desain potong lintang. Sampel penelitian ialah pasien dengan luka bakar yang dirawat di RSUP Prof. Dr. R. D. Kandou dan rumah sakit jejaring. Penilaian dilakukan langsung saat pasien masuk rumah sakit. Setiap pasien yang memenuhi persyaratan diambil data demografik dan kliniknya. Penilaian selanjutnya dilakukan pada satu bulan dan enam bulan paska tindakan perawatan awal. Hasil penelitian mendapatkan 30 pasien dengan luka bakar yang didominasi oleh pasien perempuan (63%). Derajat luka bakar terbanyak ialah superficial-middermal (67%). Penilaian POSAS oleh dokter dan pasien cenderung sama dan mengalami penurunan baik pada bulan pertama dan bulan keenam setelah tindakan dengan nilai mean skor total pra tindakan 51,3±12,1; bulan pertama 44,2±9,5; dan bulan keenam 30,3±5,9. Simpulan penelitian ini ialah evaluasi luka bakar yang menghasilkan jaringan parut akseptabel menggunakan skor POSAS menunjukkan kesamaan penilaian menurut observer dan pasien. Tindakan pencegahan pada awal pengamatan akan memengaruhi skor POSAS. Kata kunci: luka bakar; parut hipertrofi; Patient and Observer Scar Assessment Scales
Amplatzer Vascular Plug in Renal Artery Embolization: Case Serial and Review of the Literature Billy Karundeng; Richard Sumangkut; Yuansun Khosama; Djonny E. Tjandra; Michael D. Winarto
Medical Scope Journal Vol. 6 No. 1 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i1.48476

Abstract

Abstract: Embolization constitutes a safe and effective therapeutic possibility in the treatment of numerous renal pathologies whether election or urgency. The use of Amplatzer vascular plug (AVP) constitutes a more recent and less widespread therapeutic choice, and its use in the renal district is not yet widespread although potentially very valid. Perioperative renal artery embolization has been introduced to reduce the risk of oncological spread and intraoperative bleeding, in order to facilitate surgery, thus decreasing perioperative morbidity. Nevertheless, in recent literature the real usefulness of perioperative renal artery embolization is still debated. Some authors agree that the advantages of perioperative renal artery embolization are to decrease intraoperative bleeding with a lower transfusion rate and to reduce operative time. Therefore, we presented five cases of renal arterial embolizations (RAEs) performed with AVP from July to August 2022 at Prof. Dr. R. D. Kandou Hospital, Manado. In all cases, a single plug was used which perfectly adapted to the target artery resulting in complete occlusion of the vessel within a short period of time. Renal artery embolization was generally performed the day before surgery under local anesthesia. After confirmation of the tumor vascularization with a contrast study, the selective renal artery embolization was performed. In our experience, the use of AVP for the treatment of renal arteriovenous fistula and neoplastic masses had given excellent results without any complications during and after the treatment. In conclusion, RAE performed with AVP has growing potential and numerous advantages in terms of the time of the procedure, speed of embolization, and precision of occlusion, but with a relative increase in costs. Keywords: amplatzer vascular plugs; vascular surgery; endovascular surgery; renal artery embolization
Analisis Pemberian Propolis terhadap Kadar CA 15-3 Kasus Kanker Payudara Stadium Lanjut Filandy Pai; Christian Manginstar; Marselus Merung; Fredrik G. Langi
Medical Scope Journal Vol. 6 No. 1 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i1.48478

Abstract

Abstract: Breast cancer is the first rank of cancer incidence and the second mortality rate in Indonesia. Propolis is already known as a potential anticancer agent. This study aimed to evaluate the effect of propolis administration on CA 15-3 level in breast cancer patients. This was a quasi experimental study with a pre and post test design. Subjects were patients with advanced breast cancer at the Surgery-Oncology polyclinic and Surgery nursing room at Prof. Dr. R. D. Kandou Hospital Manado from June 2022 to March 2023. There were 20 patients with breast cancer in this study, divided into two groups (treatment and control groups) with age and cancer location. Data were analyzed with th independent t-test. The results showed that the increase of CA 15-3 level in treatment group was 8.3±3.5 U/mL meanwhile in the control group was 11.4±3.4 U/mL. There was no significant difference in the increased level of CA 15-3 in the two groups (p=0.069). In conclusion, propolis administration has descriptive effect on breast cancer patients with lower increase of CA 15-3 level compared to the control group, however, there is no significant difference between the two groups. Keywords: propolis; breast cancer; CA 15-3 marker   Abstrak: Kanker payudara menduduki peringkat pertama insidensi kanker dan angka mortalitas kedua di Indonesia. Propolis telah dikenal sebagai agen antikanker yang potensial. Penelitian ini bertujuan untuk mengevaluasi efek pemberian propolis terhadap kadar plasma CA 15-3 penderita kanker payudara. Penelitian ini menggunakan metode kuasi eksperimental pre dan post tes dengan desain potong lintang. Subjek penelitian ialah pasien kanker payudara stadium lanjut di Poliklinik Bedah-Onkologi dan Ruang Perawatan Bedah RSUP Prof. Dr. R. D. Kandou Manado sejak bulan Juni 2022 hingga Maret 2023. Jumlah subjek penelitian sebanyak 20 pasien, dibagi atas dua kelompok (kelompok uji dan kontrol) dengan data demografi usia dan lokasi kanker. Uji satistik yang digunakan ialah uji t tidak berpsangan. Hasil penelitian mendapatkan peningkatan kadar CA 15-3 kelompok uji ialah 8,3±3,5 U/mL sedangkan pada kelompok kontrol sebesar 11,4±3,4 U/mL. Tidak didapatkan perbedaan bermakna untuk kenaikan CA 15-3 pada kelompok uji dan kelompok kontrol (p=0,069). Simpulan penelitian ini ialah pemberian propolis pada pasien kanker payudara stadium lanjut secara deskriptif berefek dengan kadar peningkatan CA 15-3 yang lebih rendah dibandingkan kelompok kontrol tetapi secara statistik tidak terdapat perbedaan bermakna antara kedua kelompok penelitian. Kata kunci: propolis; kanker payudara; penanda CA 15-3
Perbandingan Efektivitas Daya Antibakteri Minyak Seith dengan Minyak Bawang Putih (Allium sativum) terhadap Pertumbuhan Pseudomonas aeruginosa Siti N. Aihena; Yuniasih M. J. Taihuttu; Halidah Rahawarin
Medical Scope Journal Vol. 6 No. 1 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i1.48723

Abstract

Abstract: Pseudomonas aeruginosa is an opportunistic bacterium and has the ability to withstand several types of antibiotics (antibiotic resistance). Garlic oil contains active substances such as flavonoids, alkaloids, saponins, tannins, and curcumin which function as antibacterial. This study aimed to compare the antibacterial effectiveness of Seith oil with of garlic oil (Allium sativum) against P. aeruginosa bacteria. The oil concentrations were 10%, 15%, 20%, 25%, 50%, 75%, and 100%. Antibacterial activity test against P. aeruginosa bacteria was assessed using the disk diffusion method. The results showed that Seith oil could not inhibit the growth of P. aeruginosa, meanwhile garlic oil of 50%, 75%, and 100% inhibited the growth of P. aeruginosa with the mean inhibition zone diameters of 1.38 mm, 1.88 mm, and 3.13 mm, respectively. The Kruskal-Wallis test showed a p-value of <0.01 indicating significant difference in the diameters of inhibition zones between Seith oil and garlic oil (Allium sativum) against P. aeruginosa bacteria. The Mann-Whitney U test showed significant differences between garlic oil (Allium sativum) of 100% and 75% against Pseudomonas aeruginosa bacteria, and between garlic oil of 75% and 50%. In conclusion, garlic oil (Allium sativum) is more effective than Seith oil against Pseudomonas aeruginosa bacteria. Keywords: Seith oil; garlic oil (Allium sativum); Pseudomonas aeruginosa; antibacterial effect   Abstrak: Pseudomonas aeruginosa merupakan bakteri oportunistik dengan kemampuan bertahan terhadap beberapa jenis antibiotik (resisten antibiotik). Minyak bawang putih memiliki kandungan zat aktif seperti flavonoid, alkaloid, saponin, tanin, dan kurkumin yang berfungsi sebagai antibakteri. Penelitian ini bertujuan untuk mengetahui perbandingan efektivitas daya antibakteri antara minyak seith dengan minyak bawang putih (Allium sativum) terhadap bakteri Pseudomonas aeruginosa. Konsentrasi minyak yang digunakan ialah 10%, 15%, 20%, 25%, 50%, 75%, dan 100%. Uji aktivitas antibakteri terhadap bakteri P. aeruginosa menggunakan metode difusi cakram. Hasil penelitian memperlihatkan bahwa minyak Seith tidak dapat menghambat pertumbuhan bakteri P. aeruginosa. Minyak bawang putih menghambat pertumbuhan bakteri P. aeruginosa pada konsentrasi 50%, 75%, dan 100% dengan masing-masing rerata diameter zona hambat ialah 1,38 mm, 1,88 mm, dan 3,13 mm. Hasil uji Kruskal-Wallis menunjukkan nilai p<0,001 yang berarti terdapat perbedaan diameter zona hambat yang bermakna antara minyak Seith dan minyak bawang putih (Allium sativum). Efektivitas daya antibakteri minyak bawang putih (Allium sativum) lebih besar dibanding minyak Seith. Hasil uji Mann-Whitney U menunjukkan bahwa minyak bawang putih dengan konsentrasi 100% dan 75% memiliki perbedaan bermakna (p=0,015), serta konsentrasi 75% dan 50% (p=0,040). Simpulan penelitian ini ialah daya antibakteri minyak bawang putih (Allium sativum) lebih efektif dibandingkan daya antibakteri minyak Seith terhadap bakteri Pseudomonas aeruginosa. Kata kunci: minyak Seith; minyak bawang putih (Allium sativum); Pseudomonas aeruginosa; efek antibakteri
Manifestasi Hepatik sebagai Prediktor Mortalitas COVID-19 pada Anak Suryadi N.N Tatura; Meliana Sulistio
Medical Scope Journal Vol. 6 No. 1 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i1.50323

Abstract

Abstract: Coronavirus disease-19 (COVID-19) has been associated with hepatic involvement in children, often manifesting as elevated serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels during infection. Some retrospective cohorts and case series have shown various degrees of ALT/AST elevation in with a worse disease’s outcome. Yet, the mechanism was still unknown. This study aimed to determine the association of liver involvement with the outcome of COVID-19 infection in infants and children. This was a prospective and observational study. Subjects were 96 infants and children with confirmed COVID-19 at Prof. Dr. R. D. Kandou Hospital from 1 until 31 January 2022. Patient with pre-existing liver diseases or other infections like malaria and hepatitis, were excluded. The results showed that most respondents were aged between 0 days to 17 years; 75.0% had not any comorbidities. The analysis showed that most subjects with normal ALT levels had a survived outcome (97.5%), while most subjects with abnormal ALT levels had a demise outcome (32.1%). However, about 91.5% of the subjects with normal AST levels had a survived outcome. There was a statistically significant relationship between the elevated of ALT (p=0.006) and of AST (p=0.047) variables with the outcome of infants and children with COVID-19 infection. In conclusion, liver enzyme test is a potential parameter for predicting the mortality of pediatric patients with COVID-19. Keywords: COVID-19; pediatric patients; transaminase enzymes; mortality predictor   Abstrak: Kasus Coronavirus disease-19 (COVID-19) pada populasi anak sering dikaitkan dengan manifestasi pada hepar, yang ditandai dengan peningkatan enzim alanin aminotransferase (ALT) dan aspartat aminotransferase (AST). Studi-studi observasional maupun laporan kasus sebelumnya telah menghubungkan manifestasi hepar pada infeksi SARS-CoV-2 dengan luaran penyakit yang lebih buruk, namun mekanisme dibalik keterlibatan hepar tersebut belum dapat dipastikan. Penelitian ini bertujuan untuk mengetahui hubungan antara keterlibatan hepar terhadap luaran mortalitas penyakit COVID-19 pada anak. Jenis penelitian ialah prospektif dan observasional. Subyek penelitian ialah 96 bayi dan anak yang terkonfirmasi COVID-19 di RSUP Prof. Dr. R. D. Kandou selang 1-31 Januari 2022. Pasien dengan riwayat penyakit hepar sebelumnya atau memiliki tanda-tanda infeksi akut hepar, seperti malaria dan hepatitis, dieksklusi dari studi ini. Hasil penelitian mendapatkan subjek didominasi anak usia 0-17 tahun; 75% tidak memiliki komorbiditas. Pada kelompok dengan luaran hidup, mayoritas (97,5%) memiliki nilai ALT normal, sebaliknya pada kelompok dengan luaran meninggal, 32,1% memiliki nilai ALT meningkat. Terdapat hubungan bermakna antara peningkatan kadar ALT (p=0,006) dan AST (p=0,047) terhadap luaran penyakit COVID-19. Simpulan penelitian ini ialah kadar enzim transaminase hepar dapat menjadi salah satu parameter dalam memrediksi luaran mortalitas anak yang terkonfirmasi COVID-19. Kata kunci: COVID-19; pasien anak; enzim transaminase hepar; prediktor mortalitas
Analisis Pelaksanaan Sistem Pengelolaan Limbah Medis di Rumah Sakit Daerah Kepulauan Christin Andolo; Diana V. D. Doda; Lydia E. N. Tendean
Medical Scope Journal Vol. 6 No. 1 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i1.50621

Abstract

Abstract: In general, developing countries have not yet implemented optimal management of medical waste, which causes the accumulation of medical waste. Research on medical waste management in hospitals located in the Archipelago area is still lacking, so research like this needs to be carried out. This study aims to analyze the implementation of the medical waste management system at the Islands Regional Hospital. The research method used is a qualitative method with eight informants. The research results show that in terms of human resources, there is still a lack, especially for the medical waste management section, of budgetary and financial resources to facilitate the training of medical staff, cleaning staff, procurement and maintenance of infrastructure, and investment in better waste management technology. Inadequate medical waste management methods also affect the effectiveness of medical waste management itself and can lead to an increasing amount of medical waste. The amount of medical waste generated can affect the capacity and method of treatment required. The observation results show that there are problems in sorting and containerizing medical waste where the trash for non-medical waste has been mixed with medical waste. In the temporary storage area, medical waste has accumulated a lot and has not been processed or recycled. Treatment of medical waste uses an autoclave and also incinerates medical waste manually. This is done because the incinerator is not functioning optimally. The conclusion of this study is that the medical waste management system is not yet optimal. It is hoped that the hospital, as well as health workers and cleaners, can implement an optimal medical waste management system to avoid things that can cause health problems, environmental disturbances, and ecosystem disturbances. Keywords: Waste, Medical, Non-Medical, Management. Abstrak : Secara umum pada negara berkembang belum menerapkan pengelolaan limbah medis yang optimal sehingga menyebabkan penumpukan limbah medis. Penelitian tentang pengelolaan limbah medis di Rumah Sakit yang berada di daerah Kepulauan masih sangat kurang sehingga penelitian seperti ini perlu untuk dilakuan. Penelitian ini bertujuan untuk menganalisis pelaksanaan sistem pengelolaan limbah medis di Rumah Sakit Daerah Kepulauan. Metode penelitian yang digunakan metode kualitatif dengan jumlah informan 8 orang. Hasil penelitian menunjukkan bahwa dari segi sumber daya manusia masih kurang khususnya untuk bagian pengelolaan limbah medis, kurangnya sumber anggaran dan keuangan untuk memfasilitasi pelatihan tenaga medis, petugas kebersihan, pengadaan, perawatan sarana prasarana, serta investasi dalam teknologi pengelolaan limbah yang lebih baik. Metode pengelolaan limbah medis yang kurang memadai juga berpengaruh terhadap efektivitas pengelolaan limbah medis itu sendiri serta dapat menyebabkan jumlah limbah medis yang semakin banyak. Jumlah limbah medis dihasilkan dapat mempengaruhi kapasitas dan metode pengolahan yang dibutuhkan. Hasil observasi menunjukan bahwa adanya masalah dalam pemilahan dan pewadahan limbah medis, dimana tempat sampah untuk limbah non medis sudah tercamur dengan limbah medis . Di tempat penyimpanan sementara limbah medis sudah sangat menumpuk dan belum di olah ataupun di daur ulang. Pengolahan limbah medis menggunakan autoclave dan juga melakukan pembakaran limbah medis secara manual hal ini dilakukan karena incinerator belum berfungsi secara optimal. Kesimpulan penelitian ini yaitu belum optimalnya sistem pengelolaan limbah medis. Diharapkan kepada pihak rumah sakit dan juga petugas kesehatan serta petugas kebersihan dapat menerapkan sistem pengelolaan limbah medis secara optimal untuk menghindari hal-hal yang dapat menyebabkan gangguan kesehatan, gangguan lingkungan dan juga gangguan ekosistem. Kata Kunci : Limbah, Medis, Non Medis, Pengelolaan.
Role of Colonoscopy in Foreign Body (Needle) Ingestion in Children: A Case Report and Literature Review Harsali F. Lampus; Candy Candy; Leo Rendy; Ronald Sorongku; Sabrandi P. Saputra
Medical Scope Journal Vol. 6 No. 1 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i1.51636

Abstract

Abstract: Foreign body (FB) ingestion is one of the most complex and serious emergency conditions for diagnosis that often occurs in children. Most ingested FBs, intentionally or unintentionally, pass through the gastrointestinal tract without complications, and only a small proportion require surgical intervention inter alia colonoscopy. However, if the patient complains of abdominal pain, complications may occur, especially perforation with peritonitis, and in this case a laparotomy is needed. We reported a case of a 13-year-old girl with the chief complaint of needle ingestion two weeks ago. Patient complained of abdominal pain and was unable to defecate. Plain abdominal radiographs showed needle-shaped metal density in the lower intestinal; therefore, the patient was referred to Prof. Dr. R. D. Kandou Hospital for further treatment. An endoscopy was initially performed but no foreign body was found because they might had been in the intestine. Colonoscopy revealed a foreign body in the proximal ascending colon, transverse position. Extraction of the foreign body, along with pulling the scope and evaluating the transverse, descending, sigmoid and rectum colon which were within normal limits was carried out. Monitoring after removal of the foreign body for two days found no complaints of abdominal pain and bowel movements were normal, therefore, the patient was discharged from the hospital. In conclusion, since a sharp foreign body (a needle) was still in the proximal ascending colon, a colonoscopy was performed with successful removal of the needle. Keywords: foreign body; needle; endoscopy; colonoscopy
Liposarcoma of the Thyroid Gland: A Case Report Christian Manginstar; Marselus Merung; Denny Saleh; Leise Limpeleh; Enika Tilaar; Ridel Torar
Medical Scope Journal Vol. 6 No. 1 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i1.51654

Abstract

Abstract: Liposarcoma is one of the most common soft tissue tumors in adults. Liposarcoma is usually found in retroperitoneal organs and extremities, but rarely in the thyroid gland. We presented a case of dedifferentiated liposarcoma in the thyroid gland. A 56-year-old woman with a history of a lump in her neck for ten years. Malignancy was suspected due to the local extension of the tumor, therefore, complete resection of the tumor was performed. Histopathological examination showed a dedifferentiated liposarcoma. Two months post-surgery, the patient suffered from lung and brain metastases and was treated with lenvatinib. The complaints reduced and there was no significant side effect during therapy. The treatments for liposarcoma are surgery, radiotherapy, chemotherapy, and targeted therapy. Surgery followed by radiotherapy and chemotherapy is the option in the treatment of liposarcoma. This patient underwent surgery with the histopathological result of dedifferentiated thyroid liposarcoma. In the nine-month follow-up of therapy, there were no complaint of the patient. In this case, dedifferentiated liposarcoma in the thyroid gland with metastases was treated surgically followed by lenvatinib administration gave satisfactory result. Keyword: liposarcoma; thyroid gland; dedifferentiated liposarcoma; malignant tumor
Non-Vascularized Fibular Bone Graft for Giant Cell Tumor of the Distal Ulna: A Case Report Albertus D. Noersasongko; Haryanto Sunaryo; Tommy Suharso; Andriessanto Lengkong; Rangga Rawung; Stefan Kambey; Patrick S. Arikalang
Medical Scope Journal Vol. 6 No. 1 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i1.51674

Abstract

Abstract: Cases of bone giant cell tumors (GCT) are rarely found, generally benign and locally aggressive tumors. Surgical resection is the universal standard for treatment of bone GCT. Non vascularized fibular graft (NVFG) is useful in the reconstruction of skeletal defects, especially in cases of scarred and avascular recipient sites and patient with tumor surrounded by poor tissue condition. We report a 53-year-old woman, with a lump in her left hand for three years. X-ray examination revealed a mass with firm border and regular edge that reached the epiphysis expansively with thinning of the cortex in the distal region of the left ulna. Tumor excision was performed with open reduction internal fixation (ORIF) and fibular bone graft. To date, GCT is one of the most obscure and intensively examined bone tumors, and its histological images do not predict the clinical outcome. Moreover, many unanswered questions regard to the treatment and prognosis without any consensus regarding the ideal treatment selection. NVFG osteosynthesis shows encouraging results, and adequate therapy, wound care and patient compliance affect the patient’s outcome. In conclusion, NVFG and internal fixation are effective options for post tumor excision, and osteosynthesis has encouraging result. Keywords: non vascularized fibular graft (NVFG); giant cell tumor; bone graft; ulna

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